Safest Neighborhoods in South San Francisco, CA
South San Francisco's highest safety score is 4.5 out of 5, in Westborough. 2 ranked South San Francisco neighborhoods score 4 out of 5 or higher for safety. Winston-Serra follows at 4.0 out of 5.
Houseberry scores 15 South San Francisco neighborhoods on schools, safety, amenities, price, value and appreciation. Safety scores in South San Francisco run from 1.9 to 4.5 out of 5, and 2 score 4 out of 5 or higher. Median home prices range from $1,073,200 in Orange Park to $1,577,750 in El Camino across 10 priced neighborhoods. Across the five nearest cities the average safety score is 3.3 out of 5, against 2.6 in South San Francisco.
Learn more about South San Francisco, CA.
Westborough, South San Francisco, CA
Keywords: Modern Living, Vibrant Community, Urban Convenience
Westborough in South San Francisco stands out as a dynamic neighborhood, offering a blend of modern living with a strong community vibe. Known for its diverse housing options and vibrant atmosphere, it's a popular choice for families and professionals alike. ... See Full Page
Winston-Serra, South San Francisco, CA
Keywords: Community-focused, Scenic beauty, Architectural diversity
Winston-Serra in South San Francisco is a picturesque suburban neighborhood that masterfully blends the tranquility of suburban living with the convenience of city amenities. This area, comprising Winston Manor and Serra Highlands, is celebrated for its strong community ties, scenic beauty, and accessibility. ... See Full Page
Paradise Valley, South San Francisco, CA
Keywords: Suburban Serenity, Neighborly Bonds, Tradition-Rich
Paradise Valley is a portrait of suburban serenity, where every street and home tells a story of community and longevity. It's the kind of neighborhood where traditions are nurtured, and neighborly bonds are the rule, not the exception. ... See Full Page
Sign Hill, South San Francisco, CA
(2) City data used
Keywords: Historic Charm, Panoramic Views, Community Greenspace
Sign Hill welcomes you with a historic whisper that echoes across the cityscape. Here, the homes are as much a part of the landscape as the famous hillside sign above them, offering residents a slice of history alongside modern comforts. ... See Full Page
Sunshine Gardens, South San Francisco, CA
Keywords: Friendly Suburbia, Homely Streetscape, Community Green Space
Sunshine Gardens in South San Francisco offers a slice of suburban life where community spirit and convenience intersect. This neighborhood, known for its friendly atmosphere, is characterized by its neat rows of well-kept homes and family-friendly vibe. ... See Full Page
Avalon, South San Francisco, CA
Keywords: Diverse Community, Peaceful Living, Welcoming Atmosphere
Avalon in South San Francisco is a gem of a neighborhood, blending a family-friendly atmosphere with the convenience of suburban living. It's a place where neighbors greet each other warmly and the streets resonate with a sense of community. ... See Full Page
El Camino, South San Francisco, CA
Downtown Soth San Francisco, South San Francisco, CA
(2) City data used
Keywords: Urban Energy, Cultural Hub, Historic Charm
Downtown South San Francisco, known as the "Industrial City," combines the bustling energy of urban life with a rich historical backdrop. This lively neighborhood is the cultural and commercial heart of the city, where historic charm meets modern development. ... See Full Page
Mission Road District, South San Francisco, CA
(1) Limited data(2) City data used
Orange Park, South San Francisco, CA
(2) City data used
Keywords: Community Engagement, Outdoor Enjoyment, Suburban
Orange Park in South San Francisco stands as a testament to suburban living enriched by community spirit and outdoor enjoyment. This neighborhood, with its inviting atmosphere, is a popular choice for families and individuals who appreciate a balance of leisure and convenience. ... See Full Page
East of 101, South San Francisco, CA
(1) Limited data(2) City data used
Keywords: Biotech Hub, Industrial Center, Genentech Headquarters
The East of 101 neighborhood in South San Francisco is a bustling industrial and biotech hub that is home to many of the city's most innovative companies. Bordered by the San Francisco Bay and located directly east of Highway 101, this area plays a significant role in the local economy, hosting a mix of commercial, logistical, and scientific operations. ... See Full Page
Gateway, South San Francisco, CA
(1) Limited data(2) City data used
Keywords: Commercial Hub, Proximity to SFO, Hotels & Amenities
Gateway is a prominent commercial and business-oriented neighborhood located in South San Francisco. Its strategic location near San Francisco International Airport (SFO) and major transportation hubs makes it a hub for corporate offices, hotels, and logistical services. Defined by its industrial and commercial landscape, Gateway attracts a workforce that benefits from its convenience and proximity to major highways like US-101. ... See Full Page
Lindenville, South San Francisco, CA
(2) City data used
Keywords: Industrial Hub, Proximity to SFO, Mixed-Use Development
Lindenville, situated in South San Francisco, is a dynamic and mixed-use neighborhood known for its industrial roots and growing commercial presence. Defined by its strategic location near San Francisco International Airport (SFO) and major highways, Lindenville is a hub for businesses, logistics, and commuters alike. The neighborhood's landscape is characterized by a blend of warehouses, office spaces, and small businesses, creating a functional and industrious atmosphere. ... See Full Page
Oyster Point, South San Francisco, CA
(1) Limited data(2) City data used
Keywords: Oyster Point Marina, Bay Trail Access, Biotech Hub
Oyster Point, South San Francisco, CA ... See Full Page
South Airport, South San Francisco, CA
(1) Limited data(2) City data used
Scores updated August 2026
Safest Neighborhoods
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South San Francisco safety: your questions, answered
What are the safest neighborhoods in South San Francisco?
Westborough has the highest safety score in South San Francisco, at 4.5 out of 5. The next highest safety scores in South San Francisco are Winston-Serra (4.0 out of 5) and Paradise Valley (3.5 out of 5).
Is South San Francisco safe?
Houseberry scores South San Francisco's 15 ranked neighborhoods from 1.9 to 4.5 out of 5 for safety. 2 South San Francisco neighborhoods score 4.0 out of 5 or higher for safety, led by Westborough.
Is Westborough in South San Francisco safe?
Westborough scores 4.5 out of 5 for safety on Houseberry, the highest safety score among South San Francisco's 15 ranked neighborhoods. 2 South San Francisco neighborhoods score 4.0 out of 5 or higher for safety.
What do homes cost in South San Francisco's top safety-rated neighborhoods?
Across the top 5 South San Francisco neighborhoods by safety score, the median home price is $1,273,670. Prices among those top 5 South San Francisco neighborhoods run from $1,187,800 in Paradise Valley to $1,300,510 in Winston-Serra.
Which South San Francisco neighborhoods have a high safety score at a lower price?
Westborough has the lowest median home price, $1,273,670, among South San Francisco neighborhoods scoring 4.0 out of 5 or higher for safety and priced below the South San Francisco median of $1,275,165; Westborough scores 4.5 out of 5 for safety.
Which South San Francisco neighborhoods rank highly for both safety and overall?
1 of 15 ranked South San Francisco neighborhoods score 4 out of 5 or higher for both safety and overall. Westborough leads, at 4.5 out of 5 for safety and 4.0 out of 5 overall.
How does South San Francisco compare with nearby cities for safety?
South San Francisco neighborhoods average 2.6 out of 5 for safety. The nearest cities average San Bruno 3.4, Brisbane 4.1, Daly City 2.7, Millbrae 3.3 and Pacifica 3.2.
More South San Francisco rankings
- Best neighborhoods in South San Francisco
- Best neighborhoods for schools in South San Francisco
- Best neighborhoods for amenities in South San Francisco
- Most affordable neighborhoods in South San Francisco
- Best-value neighborhoods in South San Francisco
- Fastest-appreciating neighborhoods in South San Francisco